The terms surrounding medical marijuana can be confusing. Below are some basic definitions.
No, CBD and hemp do not cause any intoxicating effects. The “high” resulting from marijuana use is caused by THC, which is just one of the many cannabinoids in cannabis. CBD is also a cannabinoid in cannabis, but it doesn’t cause any “high.” CBD and hemp products may contain trace amount of THC, but the levels are too low to cause any psychoactive effects.
How and why might some people use cannabis for medical purposes?
Harris-Taylor M. He Started Vaping THC To Cope With Chronic Pain. Then He Got Sick. NPR. December 11, 2019. https://www.npr.org/sections/health-shots/2019/12/11/776356212/he-started-vaping-thc-to-cope-with-chronic-pain-then-he-got-sick. Accessed January 29, 2020.
A 2018 study found that CBD reduced nerve-related and inflammatory pain in animals, supporting a promising future for CBD as a mainstream pain relief option. Evidence has also found that CBD is a safe effective addiction therapy, leading CBD to rise in popularity for it’s potential to treat opioid abuse and prevent it as a viable chronic pain-relieving alternative. 1
Tyndall DS. CBD Oil, the new medical elixir. NWI Times. July 13, 2018. https://www.nwitimes.com/lifestyles/cbd-oil-the-new-medical-elixir/article_eb5fb3e3-862b-59f5-a859-70dbf5057193.html. Accessed January 29, 2020.
Given the ongoing challenges of chronic pain management coupled with the consequences of the opioid epidemic, pain management practitioners and their patients are searching for effective and safer alternatives to opioids to alleviate pain. With the legalization of marijuana in many states and resulting cultural acceptance of this drug for recreational and medical use, there has been an increased interest in using cannabis for a myriad of medical problems, including pain.
Given its promising results in animal models, along with its relative safety, non-psychoactive properties, and low potential for abuse, CBD is an attractive candidate to relieve pain. Unfortunately, there is a lack of human studies about the effectiveness of CBD. However, there is an abundance of commercial advertisements about the magical effects of CBD, and it is frequently presented as a cure-it-all potion that will treat everything including diabetes, depression, cancer, chronic pain, and even your dog’s anxiety!
What’s the thinking behind using cannabis for chronic pain?
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CBD is emerging as a promising pharmaceutical agent to treat pain, inflammation, seizures, and anxiety without the psychoactive effects of THC. Our understanding of the role of CBD in pain management continues to evolve, and evidence from animal studies has shown that CBD exerts its pain-relieving effects through its various interactions and modulation of the endocannabinoid, inflammatory, and nociceptive (pain sensing) systems. The endocannabinoid system consists of cannabinoid receptors that interact with our own naturally occurring cannabinoids. This system is involved in regulating many functions in the body, including metabolism and appetite, mood and anxiety, and pain perception.
If you or someone close to you is considering trying CBD, I would recommend Dr. Robert Shmerling’s advice about the dos and don’ts in choosing an appropriate product. Until there is high-quality scientific evidence in humans, it is difficult to make a recommendation for the regular use of CBD in chronic pain management.
Cannabidiol, even in high amounts, is generally safe. Side effects from CBD may include:
Some studies suggest that CBD can have an effect on how an individual perceives pain, but more robust research is needed. CBD is generally considered a full-body treatment, which means that it does not target back pain specifically—except in the case of topical products—but contributes to an overall feeling of relaxation and pain relief.
More severe side effects, while rare, include:
Potential Risks and Side Effects of CBD
As with other natural products, there is potential for adverse reactions when taken with other medications, especially those that come with grapefruit warnings, such as certain blood thinners. These warnings indicate that certain medications should not be taken with products containing grapefruit.
Research indicates that CBD may reduce back pain by:
CBD oil is derived from a plant called cannabis sativa. The plant has over 100 chemical compounds, called cannabinoids, that have a range of effects, including anti-inflammatory and analgesic (pain relieving) qualities.
While CBD is present in both varieties, many of the CBD products available to consumers are from the hemp plant. CBD does not come with the high or psychogenic effects of marijuana.