(The Cannabiz Agency/iStock)
Though clinical and anecdotal evidence suggests CBD can help manage different conditions, CBD became most famous for treating a rare and debilitating form of pediatric epilepsy.
CBD is typically the second-most abundant cannabinoid in cannabis, but this isn’t always the case. A strain may deliver CBD and THC in the following ratios:
What are the medicinal effects of CBD?
Balanced CBD/THC strains will be a little more euphoric than CBD-dominant strains, though they’re much less likely to induce anxiety, paranoia, and other negative side effects. Strains like these tend to be the most effective for pain relief, and they’re also well-suited for THC-sensitive consumers who’d like a mellow buzz.
CBD can also block some of the intoxicating effects of THC. By binding to cannabinoid receptors, it will keep THC from activating those receptors. This translates to a less intense psychoactive effect, which is why products with a mix of CBD and THC are great for first-time consumers.
High-CBD strains tend to deliver very clear-headed, functional effects without the euphoric high associated with high-THC strains. They’re typically preferred by consumers who are extremely sensitive to the side effects of THC (e.g., anxiety, paranoia, dizziness).
If you would like to know more about the benefits of CBD, check out our CBD Guide.
“There is a great deal of interest in the possible therapeutic effects of CBD, but there is very little evidence of efficacy,” said Dr. J Hampton Atkinson, co-director of the Center for Medical Cannabis Research (CMCR) at the University of California, San Diego. CBD may have health benefits, but the lack of research in this area means there just aren’t enough data points to support most of the anecdotal claims. Along that same line, the lack of research also means the potential health risks of consuming CBD are unclear.
Within the CMCR, there is also “much interest in the possible anti-inflammatory effects of CBD, for use in arthritis of various types, including knees and hands,” Atkinson said. Recent in vitro research with human cell lines afflicted with rheumatoid arthritis has suggested that CBD treatment may help reduce inflammation.
Research on CBD
However, now that cannabis is enjoying a research renaissance by way of legalization efforts, medical science is gaining a much more detailed perspective on this popular and fascinating plant. According to
According to nonscientific anecdotal evidence, CBD is good for treating discomfort and illness of all kinds. Sufferers of everything from anxiety and aches to epilepsy and cancer are evangelizing for the CBD molecule. But the largely prohibited status of cannabis has prevented many long-term, academically rigorous studies on most cannabinoids in isolation, leaving these anecdotal claims mostly uninvestigated until recently.
Scientific observation takes time, and the research community has only just begun to pursue scientific inquiry into the discrete effects of various cannabinoids. That said, many researchers believe the potential carried by CBD is promising.
With these sorts of benefits, it’s little wonder that there’s a booming market for CBD—and readily willing suppliers promising miraculous results.
In addition to that good old “melting into a lawn chair” feeling, CBD’s reported benefits include relief from anxiety, joint pain, post-traumatic stress disorder, menstrual cramps, insomnia, nausea, seizures, bowel inflammation, and plain old moodiness. Today, adults in more than half of US states (and 16 countries worldwide) have legal access to marijuana for medical purposes, and it’s been legalized for recreational use in nine states, plus Washington, DC. As marijuana continues its march into the mainstream, CBD has emerged as an easy entryway for those who want to dip a toe into the wellness benefits of weed, but may be skeptical of getting stoned.
Recently, at the end of a surf trip with several friends, my pal Tim passed me a pipe packed with sticky green buds. I’m not much of a social smoker (more of a one-hitter-before-chores type) so politely declined.
How CBD works
CBD is one of the many chemical compounds in a class called “cannabinoids” that naturally occur in cannabis plants. While THC is the most famous of cannabinoids for its ability to get us high, CBD is a rapidly rising star for its capacity to deliver mental and physical benefits without the giggles, paranoia, or couch-lock. Eaze, a marijuana delivery service that operates in California, reported an “exceptionally high” demand for CBD in 2017, which led the company to quadruple its product offerings in the category. Chris Kelly, a representative of Tikun Olam, an Israeli company at the forefront of medical marijuana, calls Avidekel—his employer’s highest-CBD strain—the “golden child” of its offerings. Rolling Stone deemed it one of the five best strains of 2017.
I took a little hit, and soon after, felt my body pleasantly melt into a lawn chair, my ability to socialize not at all impeded. Truth told, at the end of a physically exhausting vacation and a can of Tecate, I was already pretty relaxed. But the CBD seemed to deepen that state.
This is often called the “entourage effect,” or as Lester Grinspoon, a psychiatrist and professor emeritus at Harvard Medical School calls it, the “ensemble effect.” (Like so much of the research surrounding cannabis, which is heavy on anecdotal evidence and light on hard science due to marijuana’s status as a Schedule I drug, the entourage effect is the source of healthy debate.)
“It’s a mixture of CBD, cannabidiol, THC, and the phytochemicals, the terpenoids,” Grinspoon tells High Times. “You need all three of them to get the best therapeutic effect.” For this reason, Grinspoon, Lin, and many others say that the best source for therapeutic CBD is a plant with all of its cannabinoids intact.