CBD and THC can affect how other medicines work. Always discuss possible interactions with a specialist.
Cannabis bought illegally off the street, where the quality, ingredients and strength are not known, is the most dangerous form to use.
CBD is a chemical substance found in cannabis that has medical benefits.
What are the side effects?
And it is only likely to be prescribed for a small number of patients.
“Pure” products that only contain CBD, such as Epidyolex, do not carry these unknown risks linked with THC.
Many people having chemotherapy will have periods where they feel sick or vomit.
If the above does not apply to you, do not ask a GP for a referral for medical cannabis.
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing, and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit.
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
The bottom line on cannabidiol
CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.
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Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular?
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana (one of hundreds), by itself it does not cause a "high." According to a report from the World Health Organization, "In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD."
Murnion, B. “Medical Cannabis.” Aust Prescr. 2015 Dec; 38(6): 212–215.
Medical marijuana products are available with a huge range of THC and CBD concentrations. Expert opinion states that 10mg of THC should be considered “one serving” and a person new to medical marijuana should inhale or consume no more until they know their individual response.
What research is being done for medical marijuana?
At the time this article was written, 23 states have legalized medical marijuana with varying restrictions. However, it is classified as a Schedule I substance by the Federal Drug Administration (FDA), and thus is illegal at the Federal level. In most states with legal medicinal marijuana, a prescription, authorization, or medical recommendation is required, and a card or license is issued. This allows a person to buy medical marijuana.
Fernández-Ruiz, J. et al. “Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid.” Br J Clin Pharmacol. 2013 Feb;75(2):323-33.
Epidiolex is a CBD oil extract that is undergoing clinical trials for epilepsy.
THC:CBD: Nabiximols (Sativex) is a specific plant extract with an equal ratio of THC:CBD. It is approved as a drug in the UK and elsewhere in Europe for the treatment of multiple sclerosis, spasticity, neuropathic pain, overactive bladder and other indications.