The list of conditions CBD may help with is ever-expanding. More research is needed to better understand the efficacy and range of CBD’s benefits, but it’s popularly used to manage the following symptoms and conditions:
Dravet’s Syndrome is notoriously resistant to current treatment methods. People with the condition are plagued by seizures, often up to hundreds a day, and they usually worsen as people age and can be life-threatening. Currently, treatment methods include having a child wear an eyepatch, specialized diets, and brain surgery, but all have mixed success rates.
CBD vs. THC: legality
Although THC is best known for its mind-altering euphoria, it too has important medical benefits. There’s some overlap in what CBD and THC can treat, but THC is particularly effective in relieving nausea, appetite loss, insomnia, among other symptoms. Many patients find that a balance of CBD and THC offers the best symptom relief as the two work together synergistically.
A high-CBD strain would also be a great choice for someone needing to medicate throughout the day to control pain, inflammation, anxiety, or other chronic conditions.
An easy way to think about it is that THC is defined by what cannabis makes you feel, while the effects of CBD can’t be felt. The important distinction is that, unlike THC, CBD will not intoxicate you. It also addresses one of the most common reasons people choose to use CBD—pain management.
The FDA has approved one CBD-based drug. Epidiolex is a treatment for several severe forms of rare childhood epilepsy.
As part of medical marijuana, THC helps ease things like:
How CBD and THC Affect the Body
Check your state’s laws before buying products with CBD or THC.
Harvard Health Publishing: “Answers to the top questions about cannabis extract,” “Medical marijuana.”
CBD (cannabidiol) and THC (tetrahydrocannabinol) are the most common cannabinoids found in cannabis products.
CBD directly interacts with several proteins in the body and central nervous system, a few of which are components of the endocannabinoid system (ECS) . CBD has an affinity for both the CB1 and CB2 cannabinoid receptors. Our bodies have several other receptor proteins that participate in the endocannabinoid system, such as GPR3, GPR6, TRPV1, and TRPV2, for example. CBD binds to all of these, and its possible anti-inflammatory and pain-relieving effects may occur through these pathways.
(Photo by: Gina Coleman/Weedmaps)
How CBD works
Isolate : CBD isolate is cannabidiol in its purest form: a fine white powder. This crystalline form of CBD is versatile and allows users to measure precise doses.
CBD has some other very important roles outside the ECS. For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A) in mice, which may explain its supposed effects on depression and anxiety . It also acts at the peroxisome proliferator-activated receptors (PPARs) in mice, which may indicate its usefulness in fighting inflammation.
The phytocannabinoid cannabidiol is a non-intoxicating molecule that results from the heating, or decarboxylation , of cannabidiolic acid (CBDA). Most cannabis cultivars have lower concentrations of CBD than THC. However, following an explosive discovery in 2009 , droves of CBD-rich cultivars began cropping up across the US.