But again, the flimsy regulations and conflicting laws around CBD can make it hard to ensure that your CBD product is high quality. “It’s hard, because on the Internet, it’s difficult to try to get all this information and figure out all of these things. And the FDA and others can’t close these false claims down fast enough,” Mauck says.
Ultimately, everything we do comes with a risk, Mauck says. With time and more research, the potential risks and benefits will become clearer.
Choosing a high-quality CBD product can be hard. The laws and regulations around the substance are confusing and conflicting, and it is regulated differently at the state and federal level, which complicates decision-making for consumers and physicians.
Snake Oil or Miracle Cure?
“Because CBD is not controlled, basically, it’s anybody’s guess what can be in these. And so they can claim that it’s 30% cannabidiol and otherwise pure. But if it’s not independently tested, it may have other pesticides, toxins, heavy metals,” Mauck says.
The only thing we know for sure is that purified CBD can help children and young adults with two forms of particularly rare and brutal treatment-resistant epilepsy called Dravet syndrome and Lennox-Gastaut syndrome (LGS). In June 2018, the FDA approved Epidiolex, a purified CBD oral solution for patients with these conditions. Patients reported drastically lowered seizures, and in some patients, the seizures stopped completely.
One of the concerns about CBD products is that there may be other substances at play. No rigorous safety studies have been done on “full spectrum” CBD oils, which contain a variety of compounds found in the hemp plant and not just CBD.
But for conditions like depression, anxiety, migraines, and insomnia, only preclinical and pilot studies have been conducted, the Mayo Clinic review found. Most studies have been done on rodents, not humans, so there is not enough evidence to make concrete medical recommendations.
If I were you, I’d use our Body Creme 525 CBD:CBG. It’s what I use. It offers quick relief from arthritis pain, and it’s a topical, offering quicker results. I hope this helps! -Joan
Hi Diana, I don’t know where you’ve purchased this item from. I hope you asked for the lab results of what’s in that bottle. Assuming you did, I would start with figuring out the CBD dosage per dose. It’s a 300 mg Tincture bottle, if it’s in a one ounce bottle, then most likely, there are 30 doses per bottle.’check the label. If those assumptions are correct, then one dose is only 10 mg. That’s less than my customers give their pets.
Most adults use 500-1000 mg Tinctures.
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8 thoughts on “Mayo Clinic Weighs in on CBD – offers Dosage Suggestions”
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THE MAYO CLINIC WEIGHS IN ON CBD – OFFERS DOSAGE SUGGESTIONS.
I have just received a supply of b+ pure cbd in the mail. This is all new to me. I have arthritis in my joints which includes somewhat crippled arthritic hands. I am searching for relief. The cbd oil comes in 300mg bottles. From what I read above I’m wondering is this is too much of a daily dose for me.
Cannabidiol (CBD) oils are low tetrahydrocannabinol products derived from Cannabis sativa that have become very popular over the past few years. Patients report relief for a variety of conditions, particularly pain, without the intoxicating adverse effects of medical marijuana. In June 2018, the first CBD-based drug, Epidiolex, was approved by the US Food and Drug Administration for treatment of rare, severe epilepsy, further putting the spotlight on CBD and hemp oils. There is a growing body of preclinical and clinical evidence to support use of CBD oils for many conditions, suggesting its potential role as another option for treating challenging chronic pain or opioid addiction. Care must be taken when directing patients toward CBD products because there is little regulation, and studies have found inaccurate labeling of CBD and tetrahydrocannabinol quantities. This article provides an overview of the scientific work on cannabinoids, CBD, and hemp oil and the distinction between marijuana, hemp, and the different components of CBD and hemp oil products. We summarize the current legal status of CBD and hemp oils in the United States and provide a guide to identifying higher-quality products so that clinicians can advise their patients on the safest and most evidence-based formulations. This review is based on a PubMed search using the terms CBD, cannabidiol, hemp oil, and medical marijuana. Articles were screened for relevance, and those with the most up-to-date information were selected for inclusion.
Copyright © 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.