However, research into the effectiveness of CBD oil only tested pure CBD oil, not gummies. Even for pure CBD oil, there are very few well-conducted trials backing up its apparent health benefits, although research is expected to ramp up now that laws distinguish between hemp and marijuana.
CBD Gummies are edible candies that contain cannabidiol (CBD) oil. They come in a rainbow of flavors, colors, shapes, and concentrations of CBD. Gummies offer a discreet and easy way to ingest CBD, and effective marketing campaigns by many manufacturers mean their popularity has soared among long-standing CBD users and nonusers alike.
Are there any health benefits of CBD gummies?
The main active ingredient in hemp is CBD, and CBD does not have any psychoactive properties. Instead, CBD has been credited with relieving anxiety, inflammation, insomnia, and pain, although currently there is little scientific proof that CBD works, except for epilepsy. Epidiolex Is a prescription CBD oil that was FDA approved in June 2018 for two rare and severe forms of epilepsy, Lennox-Gastaut syndrome (LGS) and Dravet syndrome. Other trials are underway investigating the benefits of CBD for Parkinson's disease, schizophrenia, diabetes, multiple sclerosis, and anxiety.
The main active ingredient in hemp is CBD, and CBD does not have any psychoactive properties. Instead, CBD has been credited with relieving anxiety, inflammation, insomnia, and pain, although “credited” does not mean proven.
Medically reviewed by Carmen Fookes, BPharm. Last updated on Sep 20, 2020.
Earlier research found fewer than a third of 84 products studied contained the amount of CBD on their labels. Some users of CBD have also failed drug tests when the product contained more THC than indicated.
Last year, the F.D.A. approved Epidiolex, a purified CBD extract, to treat rare seizure disorders in patients 2 years or older after three randomized, double-blind and placebo-controlled clinical trials with 516 patients that showed the drug, taken along with other medications, helped to reduce seizures. These types of studies are the gold standard in medicine, in which participants are divided by chance, and neither the subject nor the investigator knows which group is taking the placebo or the medication.
But without clinical trials in humans, psychologists say CBD’s effect on depression is still a hypothesis, and not an evidence-based treatment.
Is CBD harmful?
Just as hemp seedlings are sprouting up across the United States, so is the marketing. From oils and nasal sprays to lollipops and suppositories, it seems no place is too sacred for CBD. “It’s the monster that has taken over the room,” Dr. Brad Ingram, an associate professor of pediatrics at the University of Mississippi Medical Center, said about all the wild uses for CBD now. He is leading a clinical trial into administering CBD to children and teenagers with drug-resistant epilepsy.
Recently, the F.D.A. sent a warning letter to Curaleaf Inc. about its “unsubstantiated claims” that the plant extract treats a variety of conditions from pet anxiety and depression to cancer and opioid withdrawal. (In a statement, the company said that some of the products in question had been discontinued and that it was working with the F.D.A.)
Cannabidiol, or CBD, is the lesser-known child of the cannabis sativa plant; its more famous sibling, tetrahydrocannabinol, or THC, is the active ingredient in pot that catapults users’ “high.” With roots in Central Asia, the plant is believed to have been first used medicinally — or for rituals — around 750 B.C., though there are other estimates too.
CBD is advertised as providing relief for anxiety, depression and post-traumatic stress disorder. It is also marketed to promote sleep. Part of CBD’s popularity is that it purports to be “nonpsychoactive,” and that consumers can reap health benefits from the plant without the high (or the midnight pizza munchies).
This could mean that people taking anti-epilepsy drugs alongside CBD will need to adjust their dosage downward to avoid side effects, Welty noted.
This is the potential use for CBD with the most evidence after usefulness in epilepsy, but “there’s a decent gap between those two,” he said.
“That’s a problem because THC can increase anxiety. It can actually make seizures worse. Those are the sorts of things you need to be careful about,” Bonn-Miller said.
Only one purported use for cannabidiol, to treat epilepsy, has significant scientific evidence supporting it.
Potential Interactions With Other Meds
“It really is the Wild West,” Bonn-Miller said. “Joe Bob who starts up a CBD company could say whatever the hell he wants on a label and sell it to people.”
Strong Evidence for Treating Epilepsy