The main active ingredient in hemp is CBD, and CBD does not have any psychoactive properties. Instead, CBD has been credited with relieving anxiety, inflammation, insomnia, and pain, although “credited” does not mean proven.
But because most CBD products are not FDA approved, strengths and purity can vary between brands and even within the same brand, meaning that there is no guarantee that you are getting what you think you are getting.
Be aware that CBD is quite a bitter substance, and a lot of gummies contain large amounts of added sugar to disguise this taste.
Are CBD products legal?
However, research into the effectiveness of CBD oil only tested pure CBD oil, not gummies. Even for pure CBD oil, there are very few well-conducted trials backing up its apparent health benefits, although research is expected to ramp up now that laws distinguish between hemp and marijuana.
Cannabis is a plant, and there are two main types; Cannabis Indica and Cannabis Sativa. While marijuana can be derived from both types, hemp is only derived from the Cannabis Sativa family.
CBD is derived from hemp, which is almost devoid of THC. THC is the chemical in marijuana that gives you a high. By law, hemp must contain no more than 0.3 percent THC to be considered hemp, otherwise, growers are at risk of prosecution under federal law.
Medically reviewed by Carmen Fookes, BPharm. Last updated on Sep 20, 2020.
To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).
Potential drug-drug interactions with CBD include:
To use CBD oil, place one or more drops under the tongue and hold the dose there for 30 to 60 seconds without swallowing. Capsules and gummies are easier to dose, although they tend to be more costly. CBD sublingual sprays are available as well.
How to Calculate CBD Dose
CBD oil is an extract of Cannabis indica or Cannabis sativa—the same plants that, when dried, make marijuana. CBD oil is believed by some to treat pain, reduce anxiety, and stimulate appetite in the same way that marijuana does, but without its psychoactive effects. CBD has also shown promise in treating certain types of seizures.
Here are a few tips to help you find the best CBD oil:
For this study, nine healthy men took either 600 mg of CBD or the same dose of a placebo. According to the researcher, those treated with CBD had lower blood pressure before and after exposure to stressful stimuli (including exercise or extreme cold).
CBD oil may benefit those with drug addiction, suggests a 2015 review of studies published in Substance Abuse.
CBD is one of the many chemical compounds that is found in the cannabis plant—referred to as cannabis sativa. There are two primary parts of the plant that humans use. One is THC, or Delta-9-Tetrahydrocannabinol, and the other is CBD. Though they’re from the same plant, THC and CBD are quite different from each other.
Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.
“Since discovering the endocannabinoid system (ECS) in the body in the 1990s, CBD has been researched more extensively. The ECS is a central regulatory system restoring normal balance and homeostasis in a range of human physiologic systems throughout the body and brain and has cannabinoid receptors and chemicals in its function,” explains Dr. Matharu-Daley.
Can Interact With Other Medications
She adds, “[Another difference is that] CBD is derived from hemp and has been classified as a legal substance. Hemp has <0.3% THC. Conversely, cannabis plants such as marijuana are grown to have much higher levels of THC and are still illegal according to the FDA, although individual states vary as to their use.”
CBD benefits include the following:
Because CBD supplements come in so many different forms—such as oils, gummies, tinctures, and vapors—the amount that’s actually absorbed can vary drastically. This, combined with each person, will ultimately affect which (if any) CBD side effects you might experience.
The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.