Ask your doctor about using CBD to avoid negative interactions with your current medications.
Studies have suggested that CBD reduces glial cell activity. Over-activity of these cells causes increased reaction to sensation. This is a symptom of fibromyalgia.
Some people may experience inflammation, but fibromyalgia doesn’t involve tissue damage.
A lack of receptors in this system would explain the symptoms of fibromyalgia.
Be sure to take the correct CBD dosage. Going over the prescribed dose is unlikely to endanger you, but it won’t work effectively. High doses can cause confusion and sleepiness.
CBD made from marijuana has higher levels of THC, and is not federally legal. It’s only legal in states that have legalized marijuana.
Sleep in a quiet, cool, and dark room. Make sure you’re relaxed when you go to bed. Take a bath, have some tea, do yoga or meditate, or listen to soothing music.
Still, a lot of people don’t really understand what CBD oil is or how it works, and it tends to be wrapped up in the controversy over medical marijuana. That can make people hesitant to try it. There’s also a lot of confusion over whether it’s legal—but there are also some positive changes on that subject.
The substance responsible for the high associated with marijuana comes from a different substance, which is called THC (tetrahydrocannabinol.) Growers who want to maximize the plant’s high use breeds and techniques that focus on higher THC levels. Meanwhile, cannabis that’s grown for hemp is generally richer in CBD than THC, and that’s where CBD is derived from.
What Is CBD Oil?
A 2016 review published in Cannabis and Cannabinoid Research found evidence that CBD is effective in migraine and irritable bowel syndrome, which are related to fibromyalgia. It also stated that some cannabis-based treatments appeared effective for fibromyalgia. The authors stated that CBD is often preferable to patients due to the high and other effects associated with THC.
The website ProCon.org has information about which states have laws specific to CBD oil. A site called Governing maintains a map of where marijuana is legal in some form.
David Ozeri, MD, is a board-certified rheumatologist from Tel Aviv, Israel specializing in arthritis, autoimmune diseases, and biologic therapies.
While there is a still a need for larger randomized trials, Habib, a rheumatologist in Netanya, Israel, believes that the research is promising and that it is worth trying medicinal cannabis for fibromyalgia soon after diagnosis, rather than considering it as an option when opioids fail.
CB2 receptors within the body can modulate microglial cell function. One 2016 study in the Swiss journal “Cellular and Molecular Life Sciences” suggested that therapeutic strategies aimed at CB2 receptors could provide a promising treatment for inflammation. The therapeutic effects of CBD on inflammation have been documented in a range of studies, such as one published in 2015 in the journal “Bioorganic and Medicinal Chemistry.”
In addition, CBD has seems to offer neuroprotective properties and stimulate cell repair in the brain. This could improve brain function in fibromyalgia patients. CBD oil may also diminish anxiety and depressive behaviors by boosting anandamide signaling, according to results of a double-blind, randomized clinical trial published in 2012 in “Translational Psychiatry”. Anandamide is a neurotransmitter that facilitates homeostasis and balanced mood.
What the experts say
In addition to helping to ease inflammation in the body, CBD oil may reduce neuropathic pain, which arises from damaged or malfunctioning nerves. Some fibromyalgia sufferers experience neuropathic pain as one of their symptoms.
Early studies and anecdotal evidence from patients are promising and indicate that CBD oil may reduce pain and inflammation, support healthy sleep, and improve mood. Photo by: Gina Coleman/Weedmaps
“CBD oil on its own, without any other medications or treatments, typically does not give strong analgesic effects,” Liptan explained. “Successful pain relief without any additional prescription medications usually requires products that contain some amount of THC in addition to the CBD.”
The brain is one of the key areas affected by fibromyalgia, with brain inflammation contributing to pain and brain fog. Recent research suggests that microglia in the brain and spinal cord play a role in fibromyalgia. When certain cells become activated, they can contribute to inflammation by amplifying pain signaling and transmission.