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Working in collaboration with chemists and naturopaths, Sagely Naturals began formulating broad-spectrum CBD-based products coupled with potent botanicals. All of Sagely Naturals’ products are derived from organically-grown, non-GMO hemp and contain less than 0.0025% THC. Each product is then quadruple-tested by a third-party laboratory to ensure the highest quality and purity standard.

Sagely Naturals also have several CBD-based products which are available to purchase in select CVS stores and via their website. The CBD-based company was founded in 2015 by Kerrigan Behrens and Kaley Nichol. According to Forbes magazine, Sagely Naturals is the largest female-founded company in the CBD market today.

One of Sagely Naturals products available to purchase from CVS is their Relief & Recovery CBD Cream. It is available in a 2fl ounce ($19.99) and a 4fl ounce ($35.99) bottle. Sagely Naturals Relief & Recovery CBD Cream contains the company’s proprietary blend of plant-based ingredients and broad-spectrum CBD. This topical cream is designed to provide cooling relief and deep nourishment to the skin. The 2fl ounce bottle contains 25mg CBD, and the 4fl ounce contains 50mg CBD.

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Also available via select CVS stores and the CVS website is Sagely Naturals Relief & Recovery CBD Spray. It comes in a conveniently sized 2-ounce bottle and is priced at $27.99. The 2-ounce bottle contains 50mg CBD and is infused with essential oils such as menthol, peppermint, rosemary, and eucalyptus. According to Sagely Naturals, their Relief & Recovery CBD Spray is a quick-drying pick-me-up for easy use on the go.

Medterra is another big winner, as CVS announced that it would be selling the California-based brand’s topical cooling cream. The cooling cream that will be available in CVS is a combination of CBD and other certified organic ingredients. The brand claims that its cream provides users with a cooling feeling, making it ideal for sore joints and muscles.

CVS also sells Sagely Naturals Calm & Centered Cream. According to Sagely Naturals, this topical cream is designed to facilitate a sense of wakeful calm. The formula also contains Sagely Naturals proprietary blend of plant-based ingredients and broad-spectrum CBD. Plus, Sagely Naturals Calm & Centred Cream is packed with essential oils such as lavender, bergamot, and chamomile. It is available in a 4fl ounce bottle and contains 50mg CBD. Sagely Naturals Calm & Centered Cream 4fl ounce is priced at $35.99.

Soon after CVS’ announcement, one of its main rivals, Walgreens, also stated its intention to sell CBD products in its stores. This is a sure sign that CBD has entered the mainstream, just a few years after it was dismissed as nothing more than a fad and a novelty item.

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“Selling unapproved products with unsubstantiated therapeutic claims is not only a violation of the law, but also can put patients at risk, as these products have not been proven to be safe or effective,” FDA Commissioner Scott Gottlieb said in a statement in December.

There have been more dangerous situations where people turn down effective medications to use unproven products, like CBD.

CVS Pharmacy announced Wednesday that it will begin selling hemp-derived CBD products in eight states. The national drug store chain will be marketing the topical cannabidiol products, such as creams, sprays and roll-ons, as “an alternative source of relief,” CVS said in a statement to NBC News. CVS will also be partnering with a company to test and verify the quality of the CBD topicals sold in its drug stores.

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“Societies have jumped far far ahead of science,” said Dr. Margaret Haney, a professor of neurobiology at Columbia University Medical Center and director of Columbia’s Marijuana Research Laboratory. “So it’s showing up in lotions and pretty much any form of product one can use. There’s a lot of different ways one could use CBD, but the ways we have studied CBD is much more limited.”

For this reason, CVS will market the creams and salves as over-the-counter medicinal products, merchandised in a dedicated display.

Another big concern for experts is that patients will avoid proven medications in favor of CBD.

CBD, or cannabidiol, comes from the hemp plant, a close relative to another member of the cannabis family, marijuana. Both plants contain abundant types of cannabinoids, but marijuana is high in the psychoactive chemical THC, while hemp is rich in CBD, the non-psychoactive component of cannabis that has generated quite a buzz for its potential medicinal benefits.