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Here is just some of what the current evidence says.

For this study, nine healthy men took either 600 mg of CBD or the same dose of a placebo. According to the researcher, those treated with CBD had lower blood pressure before and after exposure to stressful stimuli (including exercise or extreme cold).

Anxiety

Human studies evaluating the use of CBD in treating chronic pain are lacking. Those that do exist almost invariably include THC, making it difficult to isolate CBD’s distinct effects.

CBD’s exact mechanism of action is unclear. Unlike THC, CBD has a relatively low affinity for cannabinoid receptors in the brain. These are the molecules to which THC binds to elicit its psychoactive effects.

There is some evidence that CBD interacts with seizure medications such as Onfi (clobazam) and boosts their concentration in the blood. Further research is needed.

In case you’re wondering what is CBD, exactly?, here’s a quick refresher: CBD is a naturally occurring compound present in the flowers and leaves of cannabis plants. There's no THC in it, which means it can’t get you high, no matter how much you take.

CBD topical products, like balm, ointments, and lotions, should take effect pretty immediately. Once you apply these products to your body, you should start feeling relief within about 15 minutes.

Topical forms of CBD

One question we often hear regarding trying CBD for the first time is how long it will take to have an effect on your body. According to Boris Shcharansky, the chief operating officer at Papa & Barkley, the length of time depends largely on the dosing method. Here’s a simple breakdown.

CBD oil is the top trendy ingredient on the market right now. It's so popular, in fact, that revenue from products made with CBD are projected to grow to $20 billion by 2024.

If you’ve got aches, inflammation, or other issues that you’re hoping to soothe with CBD stat, be very careful not to overdose without waiting the appropriate period of time. “Ingesting CBD is typically associated with more attentiveness, less anxiety, and less inflammatory-related pain,” explains Shcharansky. “While higher doses—over 200 milligrams—have been associated with drowsiness.”

CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and, in some cases, it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.

Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular?

Is cannabidiol legal?

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Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.

CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.