Background: Cannabidiol (CBD)-based treatments for several diseases, including Tourette’s syndrome, multiple sclerosis, epilepsy, movement disorders and glaucoma, are proving to be beneficial and the scientific clinical background of the drug is continuously evolving.
Methods: In this anecdotal, retrospective, “compassionate-use”, observational, open-label study, 12 females (age 12-24 years) with severe somatoform and dysautonomic syndrome following HPV vaccination were given sublingual CBD-rich hemp oil drops, 25 mg/kg per day supplemented by 2-5 mg/ml CBD once a week until a maximum dose of 150 mg/ml CBD per day was reached over a 3 month period. Patients’ quality of life was evaluated using the medical outcome short-form health survey questionnaire (SF-36).
Results: Two patients dropped out due to iatrogenic adverse events and another two patients stopped the treatment early due to lack of any improvement. SF-36 showed significant benefits in the physical component score (P < 0.02), vitality (P < 0.03) and social role functioning (P < 0.02) after the treatment. The administration of hemp oil also significantly reduced body pain according to the SF-36 assessment. No significant differences from the start of treatment to several months post-treatment were detected in role limitations due to emotional reactions (P = 0.02).
Objectives: To investigate the short-term effect of CBD-enriched hemp oil for relieving symptoms and improving the life quality (QOL) in young girls with adverse drug effects (ADRs) following human papillomavirus (HPV) vaccine.
Conclusions: This study demonstrated the safety and tolerability of CBD-rich hemp oil and the primary efficacy endpoint. Randomized controlled trials are warranted to characterize the safety profile and efficacy of this compound.
In the said study, the authors noted that the primary physiological function of the ECS in the skin seemed to be the regulation of the well-balanced proliferation, survival, and tolerance of skin cells.
Meanwhile, CBD may help boost the immune system. Studies have shown that cannabis is immune-modulating, which means it can bring an over- or under-reacting immune system back into balance (10 ) .
Meanwhile, a 2016 study published in BMC Complementary Medicine and Therapies showed that CBD rather than Cannabis sativa crude extracts prevented cell growth at a significant rate and induced apoptosis (cell death) in laboratory-grown, cervical cancer cell lines (8 ) .
CBD for Skin Care
No study indicates that CBD directly treats warts. Still, CBD may help those dealing with the symptoms or effects of some types of warts.
Common warts are typically harmless and eventually disappear on their own. Still, most people choose to have them removed because they find them bothersome or embarrassing.
Common warts are small, coarse skin growths that occur most often on fingers or hands. Grainy to the touch, common warts also often feature a pattern of tiny black dots, which are clotted blood vessels.
Common warts are caused by HPV (human papillomavirus). Some strains of HPV are acquired through sexual contact.
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