Taking CBD with food may help to increase the bioavailability—or absorption—of the cannabinoid. As a fat-soluble molecule, CBD readily binds to lipids. Natural fats are found in many different foods, meaning you’re likely to boost the absorption rate of CBD when you take it with a bite to eat. Some users like to take CBD before or after a hearty meal. Others prefer to compound their CBD absorption with a light snack.
Just like there is no perfect time of day to take CBD, there is no perfect schedule that works for everyone either. Some prefer to take it daily to perpetuate regular CBD levels in their bodies. Others prefer to take it as needed so it maintains its effectiveness in treating certain conditions. It all depends on your body and what you’re taking it for.
SHOULD I TAKE CBD WITH FOOD?
Like many substances, there is no “proper dosage” of CBD that will work for everyone. Factors such as weight, metabolism, and genetics can influence how much CBD one person may choose to dose. That said, doses are usually measured in milligrams, and range from around 2.5mg all the way up to a few hundred milligrams per dose in clinical settings. Another factor to consider is the method of delivery. For example, it takes longer for oral CBD and edibles to be absorbed into the bloodstream due to the first-pass effect  , while sublingual administration takes a matter of minutes. CBD topicals, on the other hand, are applied directly to the skin, where the cannabinoid does not reach the bloodstream.
Anecdotal accounts of both professional and amateur athletes taking CBD before and after performing are growing exponentially. This surge in CBD use can be partially attributed to the World Anti-Doping Agency’s landmark decision to remove CBD from its list of prohibited substances in 2018. Due to CBD’s lack of psychotropic or performance-enhancing qualities, the Agency did not feel the need to lump the cannabinoid in with THC-rich, psychotropic cannabis—which is still prohibited. This means that athletes in the NFL, Olympics, UFC, and many other major sports leagues can use CBD before and after training and events.
What most people are curious about is how much CBD they should be taking, how often they should take it, and whether or not there is an optimal time of day for it. Typically, all these questions can be answered by the statement “whatever works best for you”. But in this article, we’ll go over—in greater detail—why CBD is a substance that’s so beautifully tailored to each individual.
Looking at the dosage information for the CBD product that has been FDA approved can also be helpful. For Epidiolex, an FDA-approved cannabis-derived medication used to treat seizures in people with certain types of epilepsy, the starting dosage is 5 milligrams per kilogram of body weight. This dose can later be increased to 5 mg per kilogram of body weight twice a day.
While further research is still needed, there is some evidence that CBD may have some beneficial mental health effects. These include:
Start With a Low Dose
One report by the Centers for Disease Control and Prevention (CDC) indicated that a number of people experienced negative unwanted side effects due to CBD products that contained synthetic CBD, although the products were not labeled as containing such ingredients.
Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.
The amount of CBD found in a product may depend on different factors, including the formulation and method of administration. CBD products are available in a number of different forms including oils, capsules, tablets, nasal sprays, and gummies.