Can CBD Oil ( HEMP ) cure Toenail Fungus? The results may shock you. Fungal infections in general, and particularly the infection of a nail plate pose a considerable treatment challenge. The Topical CBD oil has antimicrobials that have the tendency to kill the fungus and is effective in some patients. Read on to know more.
Can CBD Oil ( HEMP ) cure Toenail Fungus? The results may shock you.
Fungal infections in general, and particularly the infection of a nail plate pose a considerable treatment challenge. The reasons are many; the nail plate structure, the fact it lacks reparation mechanisms (most of it is out of the reach of the immune system), the speed of its growth (slow), and the biological characteristics of the fungi.
The therapeutic properties of CBD oil have been intensively studied in the past few decades with somewhat encouraging results. Research shows it has neuroprotective properties , changes psychological response to food (obesity treatment) , can be used as a painkiller in certain conditions , and there are encouraging results in cancer treatment as well . The health benefits of CBD oil does not end here- at any given moment, dozens of preclinical and clinical research studies are conducted across the world while the body of evidence updates daily. Multiple sclerosis, HIV, opioid addiction, various psychiatric conditions, and cancer are only some of the areas CBD oil research focuses on.
But, can it treat toenail fungus? This article is all about CBD oil in the treatment of toenail fungus. Theoretical and practical concepts, research studies and experiences of people who used it for the treatment of toenail fungus.
Cannabinoids and terpenoids- a short guide through their (documented) effects
Cannabis or hemp is a plant CBD manufacturers use to extract the cannabinoids from it- substances with proven therapeutical effects for human health. The cannabinoid oil consists of two main fractions- CBD (cannabidiol) and THC (tetrahydrocannabinol). Other than those, different hemp strains contain more or less of other fractions, such as Cannabigerol (CBG), Cannabinol (CBN) and CBC (Cannabichromene). Each of those slightly differs from each other and have different health effects. Besides cannabinoids, another group of molecules also plays a significant role in hemp therapeutic properties. Those are terpenoids- aromatic compounds found in many plants, chemically quite diverse whose effects to humans reach far beyond the nose.
Using sophisticated technology, manufacturers separate the CBD from THC. The separation is needed to avoid well-known psychoactive effects and to eliminate the risk of addiction while preserving all therapeutic properties of the cannabis. The effects of CBD and THC are opposed to each other in some cases- while the CBD is used to put the appetite under control, THC stimulates it. Depending on the extraction technology used, final product- CBD oil contains more or less other fractions and no THC (the whole point of the legislation is to prevent THC spreading around as an OTC remedy).
Except the above mentioned two fractions, CBN (Cannabinol) and CBC (Cannabichromene), make significant fractions of cannabinoids. CBN is a degradation product of THC of no particular importance for health. On the other hand, CBC is a lot more interesting as it shows stronger antibacterial and antifungal effects than CBD. However, compared to conventional treatments, it’s antifungal effects are described as “mild”.
Cannabigerol (CBG), a biochemical precursor of cannabinoids mentioned above is another member of a cannabinoids family. It shows the strongest antifungal and antimicrobial effects compared to CBN and CBC .
Cannabis contains more than 100 different terpenoids as well. The distinctive smell of marijuana comes from these molecules- terpenoids are what the police dogs are trained to smell when searching for weed. Hemp strains used for the production of CBD oil are not as aromatic as marijuana; therefore they contain a lot less of terpenoids. One of these compounds is particularly known for its antifungal properties, and it’s called Caryophyllene oxide. It’s the only compound of hemp plant with antifungal properties stronger than conventional antifungal drugs. Back in 1999, a group of researchers used a sheep hoof plates to simulate human nails in order to research the antifungal properties of Caryophyllene oxide. The effects were comparable to those of the ciclopiroxalamine and sulconazole- the eradication was achieved after 15 days. This is the most important study about antifungal properties of a hemp compound after topical application .
Despite the limited data about the efficacy of CBD oil topical application in toenail fungal infections and research that suggests it’s less effective than conventional treatments, there are anecdotal reports of its miraculous effects unpaired to any other “classical” approach. However, all those reports from different forums have pretty much the same format- there’s that one guy who had a nasty infection for years, an army of doctors around him was wondering how they could help, suggesting treatments that completely failed and then, almost accidentally, he discovered the miraculous effects of CBD oil. The problem disappears virtually overnight never to return back.
Does it really works or it’s just a “gray hat” marketing campaign of affiliate associates? It depends whom you ask- people want to believe it works and that’s perfectly ok. Cosmetic defects of any kind are not something people handle very well, and toenail fungus is, for sure, one of those things that hurt the self-esteem more than a toothache will ever hurt.
To try it or not to try it?
So, is a CBD oil pure extract, or it contains other fractions? The whole process of CBD production turned into a lucrative business in the last 10 years. Some estimates say that CBD market net worth will reach $2.1 billion by 2020. Legislation has not yet reached the level of “minor sub-fractions.” The chances are, in the next few years, “highly specialized” blends will be introduced to the market (it’s already happening in cancer treatment), and until that happens using commercially available CBD oil seems to be the only option.
Having in mind the treatment is safe and, practically without any side effects, it’s worth trying. At this moment, it’s safe to experiment with it- the chances are it won’t do much, but… There’s always a glimpse of hope it might work in your particular case.
Despite not so optimistic expectations at this moment, the chances are we will witness a novel and very effective CBD oil treatment of toenail fungus in the coming years. Until that happens, keep an eye on research studies!
 Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: implications for the treatment of acute relapses of multiple sclerosis. Achiron A, Miron S, Lavie V, Margalit R, Biegon A J Neuroimmunol. 2000 Jan 3; 102(1):26-31.
 Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: preclinical and clinical data. Carai MA, Colombo G, Maccioni P, Gessa GL CNS Drug Rev. 2006 Summer; 12(2):91-9.
 Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. Berman JS, Symonds C, Birch R Pain. 2004 Dec; 112(3):299-306.
 Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (review). Bifulco M, Laezza C, Gazzerro P, Pentimalli F Oncol Rep. 2007 Apr; 17(4):813-6.
 John M. McPartland DO, MS & Ethan B. Russo MD (2001) Cannabis and Cannabis Extracts, Journal of Cannabis Therapeutics, 1:3-4, 103-132.
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 Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364.
Does CBD Oil Cure Toenail Fungus?
Toenail fungus is referred to as onychomycosis in medical terms. It mostly affects the big toenails and is rarely seen on fingernails. This condition is difficult to treat and takes a long time to get cured. It leads to whitish-yellowish discoloration of the nails affected. The nails also become thick, brittle or fragile and out of shape. This causes the nail to become detached from the nail bed. It mostly occurs in people who have a suppressed immune system. Toenail fungus is caused by dermatophytes or fungus that infects the skin most of the times. The other causative agents include yeast or mold as well. (1)
Toenail fungus is not a serious condition and it goes away with treatment in healthy people. However, in people with a weak immune system, the skin surrounding the toenail fungus is prone to bacterial infections. It is best to take preventive measures in order to avoid onychomycosis. Since fungus grows in wet and damp places it is necessary to keep the feet dry after taking bath or washing feet, not wearing very tight shoes and letting the feet breathe as often as possible by wearing flip flops or slippers often and not sharing towels or socks with other people. (2)
Does CBD Oil Cure Toenail Fungus?
Cannabis is known to have anti-inflammatory and anti-microbial properties thus making it effective against toenail fungus. Some studies have shown that cannabis is capable of getting rid of toenail fungus but not as effective as the conventional methods of treatment. Although they have fewer side effects and faster mode of action research still has not completely proven their efficiency. Studies have shown that they help in relieving the pain caused by the infected nail. Since the fungus eats the affected nail and exposes the underlying tender skin it becomes extremely painful and uncomfortable while walking. The CBD oil is helpful in soothing the inflamed skin and making it easier to walk and it has also shown to hasten the healing process of the infected toenail and provide relief from pain as well. (2)
The role of cannabis in curing toenail fungus is still under research and study. There is little data available regarding its efficiency and therefore it is not prescribed commercially by the doctors. They prefer to use conventional methods to get rid of toenail fungus that is rather difficult to treat and takes a long time to get cured. In many cases, patients have reported relief by using CBD oil directly on the infected part that led to the fungus completely dying off. The drawback to this was that the fungus returned on discontinuation of the treatment. Patients who do not respond to conventional methods of treatment have tried cannabis oil and the results have varied from person to person. Some had a better response to the treatment while in others the fungus remained as such with temporary relief or no relief at all. Topical antifungals have shown less efficiency against persistent fungal infections. Oral antifungals along with topical use have shown better results. (2)
The results of anti-fungals and anti-microbials have also shown varied results in different people due to development of resistance against the anti-fungals. It is due to this reason that most treatment options available are ineffective and take a long time to get cured. Topical CBD oil has antimicrobials that have the tendency to kill the fungus and is effective in some patients. It is better to prevent the fungus from growing in the early stages and take proper measures when the person is more prone to toenail fungus. Diabetics, people with suppressed immunity, patients undergoing cancer treatment, heart patients are more prone to developing toenail fungus and therefore should take measures from the starting to avoid severe fungus from growing. Wearing properly fitted shoes, drying up feet thoroughly before putting on footwear and avoiding sharing of towels and socks can help prevent toenail fungus.