CBD restores normal brain rhythms. It does not do this by a direct effect on cannabinoid receptors, however. It acts via the endocannabinoid system. CBD antagonizes the GPR55 receptor at excitatory synapses  in the brain and inhibits the chemical messengers thus calming seizure activity. The GPR55 receptor is one of the endocannabinoid receptors involved in CBD communication between cells and are part of the endocannabinoid system.
The Lineup At A Glance
The company also provides third-party testing of all of its products guaranteeing safety and quality.
CBD Oil for Non-Epileptic Seizures
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The two main cannabinoid treatments for seizure are THC and CBD. The Food and Drug Administration (FDA) only recognizes Epidiolex, a purified CBD isolate, as an approved form of treatment for two forms of epilepsy, Dravet Syndrome & Lennox Gastaut Syndrome (LGS). Gastaut Syndrome and Dravet Syndrome  are each a form of epilepsy where using CBD has been shown to make a significant positive difference for many people.
They third-party test all of their products to guarantee freshness and purity to their customers and even provide a downloadable version of their test to any given location.
The current therapy for seizure control fails to control seizures in 30-40% of patients  , leaving an unmet need for other viable treatment options for this disorder. Not only is there a high failure rate, but the side-effects to classical seizure treatment is often felt to be worse than the seizures themselves. It is no wonder that many people have turned to CBD as a potential, alternative treatment option for epilepsy and seizures.
With such a wide potency range, CBDistillery oils may suit both novice and experienced consumers alike. The only downside to the company’s product range is that they’re not made with organic hemp.
Epilepsy compromises all aspects of a person’s daily life. The violent tremors caused by a seizure attack can put the individual in grave danger, not to mention that people with epilepsy are also prone to suffer from sleep issues, migraines, anxiety disorders, and depression.
Does CBD Oil Work for Seizures?
While scientists still don’t know exactly how CBD oil works for seizures, they’ve observed the following interactions which may explain the positive effects:
Considering the factors above, such as body weight and metabolism, adults with epilepsy need more CBD in their regime than children. Use the following guidelines to reach an effective dose:
Before receiving the FDA’s approval, Epidiolex went through three randomized, double-blind, placebo-controlled clinical trials examining 516 patients with either syndrome. When administered along with other medications, Epidiolex successfully reduced the participant’s frequency of seizures compared to the placebo group. Besides, CBD improved other associated symptoms for the participants, such as sleep and anxiety.
Though all forms of epilepsy involve seizures, having a seizure doesn’t mean you have epilepsy. According to the National Institute of Neurological Disorders and Stroke, you must have at least two seizures to be diagnosed with epilepsy. There are many kinds of seizures, and people with epilepsy may have more than one type.
Epidiolex passed enough safety thresholds to warrant FDA approval. In the two NEJM studies, side effects tended to be mild to moderate, with difficulty sleeping, lowered appetite, and diarrhea topping the list. Some participants also had abnormal results on liver function tests, especially at the higher dose (20 milligrams per kilogram).
Epilepsy vs. seizures
CBD has been studied as a treatment for sleep problems, anxiety, and pain in a wide range of doses, from 1 mg per day to 400 mg per day or more. Higher doses can lead to side effects like sleepiness (and can be expensive), so experts generally recommend using CBD at the lowest effective amount. A study published in 2019 in The Permanente Journal, for instance, dosed participants with 25, 50, or 75 mg/day.
Epidiolex is a liquid solution. When buying on your own, you’ll encounter oils that can be ingested, tinctures to put under your tongue, creams applied on your skin, CBD edibles like chocolate and CBD gummies, as well as inhalable CBD products (vaping, but this can be dangerous and lead to EVALI, a vaping-related lung disease). For seizures, something other than topical products would probably more useful, says Lee.
But you’re not finished yet. Not only will you have to choose among forms, but you’ll also have to decide which ingredient formula you would like. There are three main ones: