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In one animal study [3] , cannabidiol or CBD acted as a weak or partial agonist on PPARγ receptors. This interaction caused vasorelaxation or widening of the aorta (a heart artery) which could lead to lower possible lower blood blood pressure.

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We wouldn’t go that far. Hypertension is a risk factor in heart attack, stroke and type 2 diabetes. Even though it’s common, it’s a serious issue which require medical attention.

Many of the cannabidiol products you’ll see in CBD stores or online are of lower quality, since – as with any product – it’s more expensive to produce high-end merchandise and it sells for a higher price, often with lower profit margins for the vendors.

What is Hypertension?

As Park explained, high blood pressure can be caused by many factors. Fortunately, there are several health benefits of CBD that could indirectly help with hypertension.

According to the National Institutes of Health (NIH), acute pain can lead to high blood pressure. Because CBD acts on the pain receptors in the brain, the pain-relieving properties of CBD could lead to decreased blood pressure.

In a famous 2017 randomized crossover study led by British doctor Khalid Jadoon and published in the Journal of Clinical Investigation (JCI), a single dose of 600 mg of CBD oil or a placebo was administered to nine healthy volunteers. The resulting data showed that acute administration of CBD reduced resting blood pressure compared to placebo dosing.

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While these studies show us an optimistic light for CBD’s future, it’s important to mention the risks involved with any natural chemical compound. We don’t yet have enough conclusive evidence to determine that CBD is an effective treatment for any condition other than the ones approved by the FDA. Most evidence has been gathered through healthy volunteers or through animal studies, both of which implies we may see different results with an ill human subject. Combination of CBD with other high blood pressure medication is the biggest potential concern if you plan on using CBD for your hypertension. If you are already prescribed high blood pressure medication, taking CBD in combination can lower your blood pressure too much. “Too low” is just as bad as “too high,” so you’ll want to speak with your physician before adding CBD onto the medication you’re already taking. Your doctor may want to reduce the dosage strength you’re taking for your other blood pressure prescription before incorporating a CBD oil into your daily regimen.

The best part about using CBD oil for high blood pressure is that because you’re ingesting it to get relief from hypertension, you’re also reaping all the other benefits it can provide.

In a randomized, double-blind, and placebo-controlled crossover study of healthy volunteers, nine males were either given a placebo or 600mg of CBD. They used a laser Doppler and a finometer to monitor cardiovascular parameters of the volunteers. In the study, cannabidiol maintained cardiac output and reduced resting systolic blood pressure. The subjects that took the real dose of CBD had a lower blood pressure count, increased heart rate, and a decreased stroke volume. Though more research is vital before we can establish that CBD has a role in some cardiovascular disorder treatments, the study’s data shows that precise administration of cannabidiol can reduce both the resting blood pressure and blood pressure caused by an increase in stress to humans.

Finding the supplements could be used safely even in such high doses, they also tested daily pill doses for 1,200 and 1,500 milligrams for up to four weeks. In addition, sublingual dosing through a 2.5mg dose of CBD spray was used safely for two weeks.