Reviews and meta-analyses of cannabinoids found the following:
There are many other medicines that should not be taken with CBD. Doing so may increase the effects of those medicines. As an example, taking CBD with medicines that cause drowsiness may cause the person to be even more sleepy.
An animal study found transdermal CBD lessened the pain and inflammation of arthritis.
CBD and Medicines
Already tried CBD? There are many other ways to reduce back pain or insomnia that do not involve taking it. Learn about some other methods that Goodpath's integrative medicine approach uses to reduce your symptoms here:
An app was used to measure changes in insomnia in over 400 people taking medical cannabis. The average symptom severity was reduced by 4.5 points on a 10-point scale, a significant improvement in insomnia.
By acting on the ECS, CBD may have many different effects on the body. Examples include: balancing the body’s overall physical functions (homeostasis), reducing pain sensation, and lessening the body’s reaction to injury or infection (inflammation).
There are also studies of oral, topical, and inhaled CBD for use in many other conditions including: dystonia (movement disorder), Fragile X syndrome (rare genetic disorder), graft-versus-host disease (bone marrow transplant rejection), multiple sclerosis (MS), opioid withdrawal, schizophrenia, and smoking cessation. CBD is also used to alleviate Parkinson’s symptoms, but there are some studies that advise against it.
 Bergamaschi MM, Queiroz RHC, Chagas MHN, de Oliveira DCG, De Martinis BS, Kapczinski F, et al. Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol. 2011 May;36(6):1219–26.
 Wheeler M, Merten JW, Gordon BT, Hamadi H. CBD (Cannabidiol) Product Attitudes, Knowledge, and Use Among Young Adults. Subst Use Misuse. 2020 Feb 24;1–8.
 Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18–041.
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CBD likely has a dose-dependent effect on sleep—it appears that low doses are stimulating and keep you awake, but larger doses have a sedating effect and can improve sleep time and wakefulness during the night.[16,17] But scientific evidence behind these effects is limited and the mechanism behind them is not yet clear. Further trials are warranted, and until then, check out these proven ways to improve your sleep.
 Babson KA, Sottile J, Morabito D. Cannabis, Cannabinoids, and Sleep: a Review of the Literature. Curr Psychiatry Rep. 2017 Apr;19(4):23.
Such results aren’t always clinically relevant, however. Another study found that, while CBD was effective in reducing chronic pain by about 1.5 points on an 11-point pain scale, such a change was likely not large enough to make a clinical difference in patient outcomes. So, again, these promising preliminary results warrant larger, higher-powered studies.
CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing, and depends in part on whether the CBD comes from hemp or marijuana. The legality of CBD is expected to change, as there is currently bipartisan consensus in Congress to make the hemp crop legal which would, for all intents and purposes, make CBD difficult to prohibit.
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Is cannabidiol legal?
CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.
CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.